FDA Slaps Extreme Caution Warning On Tricyclic Anti-Depressant, Norpramin

Although Norpramin is not much used these days, the FDA and Sanofi-Adventis today announced a Dear Doctor letter would be sent out detailing very serious problems with the tricyclic's use in some people.

"The new safety information states that extreme caution should be used when this drug is given to patients who have a family history of sudden death, cardiac dysrhythmias, and cardiac conduction disturbances; and that seizures precede cardiac dysrhythmias and death in some patients."

That says it all.