November 30, 2009

More Reports Of Kids Taking Medical Marijuana For Autism

I'm intrigued by these press accounts that keep cropping up concerning parents turning to medical marijuana to address their children's autism irritability. From what I gather, it's pretty clear that these kids aren't responding to atypical antipsychotics such as Risperdal and Abilify, both approved for autism irritability and the parents are turning to marijuana out of desperation. The pot is usually ingested as opposed to being smoked.

In the most recent account I've run across, a mother claims that medical marijuana saved her son's life.

I doubt very much that any of us in California who voted to legalize medical marijuana in 1996 (I still lived in my native land then) had any idea that the day would come when kids would be ingesting pot for autism and, even more unexpectedly, ADHD. We thought it would all be about helping AIDS and cancer patients and people with glaucoma. But if pot works for autism, then it works for autism. And for people who are concerned over giving kids pot, I'd remind them that the antipsychotics used on these same kids are well known to cause all manner of health problems.

It sure would be nice to see some research on all of this--a Risperdal versus pot clinical trial--but as things stand now the feds will never permit it.

Posted by Philip Dawdy at November 30, 2009 10:32 AM
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Me thinks once Big Pharma gets involved laws will be changed accordingly.

Posted by: BorderlineNOS at November 30, 2009 12:43 PM

I agree with Borderline. I'm actually surprised Pharma hasn't tapped this cash cow already.

Posted by: Meg at November 30, 2009 01:30 PM

http://clinicaltrials.gov/ct2/show/NCT00397605?term=marijuana+vs+antipsychotic&rank=3

US National Institutes of Health

Cannabinoids in Bipolar Affective Disorder

are many chemicals (called cannabinoids) found in cannabis but two particular ones appear to have medicinal (therapeutic) effects. These two compounds are: delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). These cannabinoids appear to have mood, anxiety, and sedative effects as well as have antipsychotic and anticonvulsant properties. This study will try to find out if these cannabinoids can be of benefit as an add-on treatment in bipolar disorder and what effects it has on thinking power and memory.

Primary Outcome Measures:
To determine whether a standardized plant extract of cannabis containing a 1:1 ratio of THC & CBD can alleviate bipolar mood symptoms unresponsive to standard treatment. To be measured weekly over 13 weeks. [ Time Frame: 13 weeks ] [ Designated as safety issue: No ]


If it's approved for bipolar it will be for autism, (and everything else)

---
http://clinicaltrials.gov/ct2/show/NCT00588731?term=cannabinoids&rank=21

Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia

(Zyprexa/Risperdal)

This study is a six-week, randomized, placebo-controlled, parallel group, fixed dose trial comparing cannabidiol Vs. placebo added to a stable dose of olanzapine or risperidone in patients diagnosed with schizophrenia. We hypothesize that adjunctive CBD treatment in antipsychotic-treated schizophrenia patients will result in an improvement in verbal short term memory as measured by increase in total immediate recall score on the HVLT.

Here's the deal: if they rx antipsychotics like Risperdal to autistic kids and the drug was created for schizophrenia...no reason why this (for example) can't be used on autistic kids/adults.

Cannabidiol is an experimental drug, Yale is the place and the sponsor is Stanley Research Institute (Fuller Torrey SZ-brain collector fame)Yale University Dr.Mohini Ranganathan, MD might have an answer or theory or something like that.
--

http://clinicaltrials.gov/ct2/show/NCT00309413?term=cannabidiol&rank=1

A Clinical Trial on the Antipsychotic Properties of Cannabidiol


Posted by: Stephany at November 30, 2009 02:53 PM

Well, this is interesting. Doctors have been telling people for years that pot can cause psychosis in susceptible individuals. I don't know how many lectures from drug squads I have sat through while my son was enrolled in an early psychosis program. It was funny because the doctors were against the use of recreational mind altering drugs while at the same time prescribing mind altering drugs for their patients. If this becomes acceptable practice for treating childhood autism, what does this say about the accepted wisdom that pot causes schizophrenia? I think it would blow it wide open.

Posted by: Rossa Forbes at November 30, 2009 11:41 PM

If my child had a problem I would do the same.
Congratulations to this parents that are aware that there is nothing available on the market to help their children.
So psychiatry is not of any help since they only work prescribing according to what the pharmaceutical industry says.
This is sad!

In the meantime psychology has turned into a joke and talking therapy disappeared.

Sad and dangerous age to have any emotional crisis.

Posted by: Ana at December 1, 2009 01:53 PM
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