November 12, 2009

British Government To Limit Antipsychotic Use For Dementia

Bloomberg today reports on the British government taking steps to drastically reduce the use of antipsychotics in treating elders with dementia. A recent report estimated that upwards of 1,800 Brits die each year after getting the drugs for dementia and another 1,620 suffer strokes. Keep in mind that all that dementia-Rxing would be off-label bother in the UK and USA.

"About 180,000 elderly people with dementia in the U.K. are given the antipsychotic drugs each year, and just 20 percent improve because of the treatment, Banerjee said at a press conference in London. As many as two-thirds of the patients don’t derive any benefit from the pills, which boost the risk of early death and carry a range of side effects including sedation, stiff muscles, and trouble thinking and speaking clearly, the report found.

"'We need to be sure that only the people who benefit from these drugs get them, and they get them at the lowest possible dose for the shortest period of time,' Banerjee said. 'It is clear that these medications are being prescribed to deal with behavior and psychological symptoms in dementia rather than just for psychosis,' he wrote in the report."

I bet it's going to be really tough to turn that ship around. Here in the US about 25 percent to 30 percent of atypical sales are for off-label use in dementia even though the drugs carry black box warnings concerning their use in dementia.

I'm glad the UK has caught some sanity on this issue. I hope the US is next.

Posted by Philip Dawdy at November 12, 2009 10:53 AM
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Comments

I'm glad a government official said these things in public -- especially that patients only 'improve" in 20% of the cases (they do?!) -- but I'm afraid that's probably as far as it's going to go as you imply. It's obscene what's going on in the name of "treatment."

Posted by: Sara at November 12, 2009 11:01 AM

A few years ago, the FDA issued a "black box" warning for a 60-70% increase in MORTALITY for the use of these drugs off-label in elders. Even mortality does not deter these people.

Posted by: Eileen at November 12, 2009 11:43 AM

If only that communicable strain of sanity had reached U.S. shores ...

Posted by: Puckett at November 13, 2009 06:00 AM
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