March 09, 2009False Data, Publication Forgery And More Rocks AnesthesiologyAs I've interviewed researchers over the last couple of years, some of my sources have told me that not only was psychiatry a mess with huge conflicts between Big Pharma and researchers, but that other branches of medicine were just as screwed up. Now, via Anesthesiology News comes a total scandal--a well-known doctor who allegedly committed acts of data falsification and publication forgery. Now, almost two dozen of his published papers are being retracted by several anesthesiology journals. (The details are over at Pharmala.com, as the original website requires a log-in for read the article.) "Scott S. Reuben, MD, of Baystate Medical Center in Springfield, Mass., a pioneer in the area of multimodal analgesia, is said to have fabricated his results in at least 21, and perhaps many more, articles dating back to 1996. The confirmed articles were published in Anesthesiology, Anesthesia and Analgesia, the Journal of Clinical Anesthesia and other titles, which have retracted the papers or will soon do so, according to people familiar with the scandal (see list). The journals stressed that Dr. Reuben’s co-authors on those papers have not been accused of wrongdoing." When you read details like these, you know the big hand of Big Pharma cannot be far away: "A cornerstone of Dr. Reuben’s approach has been the use of the selective cyclooxygenase-2 inhibitor celecoxib (Celebrex) and the neuropathic pain agent pregabalin (Lyrica), both manufactured by Pfizer. Dr. Reuben has received research grants from the company and is a member of its speakers’ bureau. However, a source told Anesthesiology News that Pfizer recently alerted its speakers to remove any reference to Dr. Reuben’s data from their presentations. Pfizer was unable to comment by the time this article went to press. The company has not been accused of wrongdoing in the matter. This is a huge scandal, one that I hope gets broader press attention. It also makes me wonder if there is any branch of medicine with clean hands. Feel free to speculate in comments. Posted by Philip Dawdy at March 9, 2009 12:01 AM
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Honestly, I am glad to see these things come to light in specialties other than psychiatry. There have been many times I felt that others blow off the psychiatry scandals with one of two excuses: either the patients are "making it all up" (like withdrawal symptoms, etc.) because what can you expect from mental patients (sarcasm alert!), or they discredit the doctors by saying "well, of course psychiatrists would do underhanded things--they'll do anything that might help them prove they are REAL doctors, even to making up research data etc., or we all know psychiatrists are all nuts that's why they went into psychiatry to begin with, so who wouldn't expect them to do stuff like this, with the power trips and narcissism, etc." (sarcasm alert again). I don't believe either of those things as a generalization, but I know many people who do, and they have been the foundation for many rationalizations about why the "general public" doesn't need to care all that much about the psychiatry scandals. To see this happening in other specialties brings welcome credibility to what is happening in psychiatry. Yes, we've seen things like the Vioxx scandal, the Vitorin mess, and the HRT debacles. I hate to see any of this happening at all, because first and foremost it all hurts the patients, and the scandals hurt the medical professionals too, the honest ones who are trying to help, who depend on journals and CME for their livelihood, the ones who CARE. And yes, they are out there. I hate to see it happening, but the more this stuff comes to light across specialties, the more chance I see that something can be done to make it stop. I wish I knew what that was, but at least a shake up might make it come faster. So in a sad, weird way, it is comforting to me to know that we (who see what is happening in psychiatry and despise it) are not alone. In the long run, I think that will help our causes. Posted by: InTheWild at March 9, 2009 05:29 AMIf you think this is big news? Someone should take a serious look at the research defining the risk of second hand and now third hand tobacco smoke. Its like a traveling medicine show with all the familiar confidence racket plugs built into the process.
Another, out-of-psychotropic, area, is cardiology. I believe I read somewhere that Grassley is going to train his laser eyes on that field - most likely to uncover the same fraud and abuse both in pharma and surgical procedures and devices. It's everywhere, have no doubt. But I will still with psychotropics - there is plenty, if not way too much, to do right in this field. Posted by: anonymous at March 9, 2009 02:13 PMMost of us think of anesthesiologists as the guys and gals who knock us out for surgery. These days, they're just as likely to specialize in "pain management" for folks with chronic ailments and unfixable injuries. The scramble to write scripts for expensive, on-patent drugs is intense; the profits are huge, and the dangers are many. Celebrex just barely escaped being yanked from the market along with its fellow Cox-2 inhibitor Vioxx. It probably should have been. Lyrica is a close cousin of Neurontin, which came into its own just when Neurontin was going off patent and its massive irresponsible off-label marketing was finally being exposed. Cymbalta is also being prescribed in bushels by these pain specialists -- generally with NO warning or awareness of its psychoactive properties and risks. "Multimodal analgesia" is just a fancy phrase meaning "treating pain with a variety of things." In other words, with cocktails of pills whose effectiveness is overhyped and whose risks are skilfully underplayed -- but which can be relied on to cost a bloody fortune. If you think depression and anxiety are big juicy markets, how about arthritis and back pain? It's not only in psychiatry that for-profit medicine is draining our bank accounts and threatening our health. It's just a tad bit easier to do in psychiatry, because the patients' reports of their own experiences are, by definition, not to be listened to. If only unwilling arthritis patients could be medicated by court order! The profits would be awesome... Posted by: Johanna at March 9, 2009 07:24 PMPost a comment
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