March 26, 2009

Antipsychotics Now Top Revenue Producers In US, Topping Cholesterol Drugs

Seriously, folks, the Rubicon has now been crossed. IMS Health reports that in 2008, sales in the US of antipsychotics (used for absolutely every alleged mental disorder under the sun) in 2008 reached $14.6 billion, topping lipid regulators (ie, statins, etc.) which hit $14.5 billion in US sales. Follow the above link and click on "top therapeutic classes by US sales.

Lipid regulators are usually the top revenue producers in the US, so this is big news and tells you a whole lot abotu how successful the off-label marketing campaigns of makers of the atypical antipsychotics have been. US sales of antipsychotics in 2004 amounted to $9.6 billion, marking 52 percent growth in four years.

I can assure one and all that America didn't suddenly develop millions of more people with psychotic disorders. These drugs are being used for depression now and that's where I bet the sales boost came from. America is no longer "Prozac Nation." It's not "Atypical Nation." And that ain't good.

It'll be interesting--and discouraging--to see how many new cases of diabetes and neuroleptic malignant syndrome crop up as a result.

Anti-depressant sales were $9.6 billion, up a bit from 2007's $9.4 billion. That's kind of impressive growth considering that most anti-depressants are now available in generic forms.

Posted by Philip Dawdy at March 26, 2009 12:07 AM
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Comments

Does the fact that antipsychotics are so expensive have anything to do with this?

Posted by: David at March 26, 2009 06:44 AM

Glad to see Zyprexa wasn't the number one atypical. Seroquel was.

Posted by: anonymous at March 26, 2009 10:57 AM

It totally does, David! Antipsychotics are the #1 top class of drugs by sales -- but they don't even make the top 15 list by numbers of prescriptions.

However, two individual antipsychotics make the Top 15 list for prescriptions of a single drug: Seroquel is #5 and Abilify is #12. Two antidepressants make that list: Effexor XR and Lexapro. Probably the most expensive ones, natch.

Posted by: Johanna at March 26, 2009 11:10 AM

While it is true that the new atypical antipsychotics are being used for depression [they are half SSRI], it is also true that the number of people diagnosed as "bipolar" has also increased.

Here is what www.SSRIstories.com has to say about this.

http://www.ssristories.com/show.php?item=1319

Second sentence of second paragraph reads: "Without the need for an episode of hospitalization for mania, estimates of the prevalence of bipolar disorder have increased significantly from 1% in 1994, to 2.6% in 2005."

With the population of the U.S. now at 300 million, the rate of bipolar disorder has increased by 4.8 million people in the U.S. in the last 11 years. It is the opinion of SSRI Stories advocates that the majority of this increase has occurred because of the massive antidepressant use in this country. People are going "manic" on their antidepressants and then being diagnosed as "bipolar".

http://www.pharmaceutical-business-review.com/article_feature.asp?guid=7C5EF4E7-F53F-41C3-BD5A-E637D0211BFD

New hope for manic-depression sufferers comes from unlikely source
21st November 2006
By PBR Staff Writer


Posted by: Rosie at March 26, 2009 11:13 AM

Antipsychotics are being prescribed to many people having adverse reactions to antidepressants -- what a racket! But seriously this is a frightening statistic.

Posted by: Sara at March 26, 2009 11:42 AM

Rosie said 'People are going "manic" on their antidepressants and then being diagnosed as "bipolar".'

That's what happened to me and of course the medical response was to claim this was merely the first appearance of my pre-existing condition. There was no evidence to support that conclusion and, with one exception, all my manic episodes were immediately preceded by treatment for depression. Nothing like manufacturing lifelong customer relationships!

Posted by: Francesca Allan at March 26, 2009 12:30 PM

The comment about how damned expensive the atypicals are hits the mark. In just this last year, Zyprexa has increased in price by over 10%!!

Posted by: Tony at March 26, 2009 01:33 PM

The real cost of these meds is just pennies of the dollars you pay for them.
And when the profits from pills go down, where should Pharma next look for profit? This PriceWaterhouseCoopers pdf says the next big cash cow should be vaccines.
http://www.pwc.com/gx/eng/about/ind/pharma/pharma2020final.pdf

Posted by: Lilly NC at March 26, 2009 02:58 PM

Yes, you need to go by prescriptions, not by sales. The only psychiatric drug I saw on the prescriptions list was Xanax (alprazolam). You can't go by sales which include institutional sales.

Philip Dawdy reponds: both sets of data are relevant.

Posted by: alex at March 26, 2009 04:54 PM

Zyprexa goes off patent in 2011. Betcha' they will pull a Seroquel XR move and try to have its purpose extended to some other thing. Wonder what they'll pick?

Posted by: anonymous at March 27, 2009 05:51 PM

I am having restlessness and sleeplessness on Abilify at 10 mg. Should I discontinue it or decrease dosage? Taking is for bipolar and major depression not totally helped by antidepressants.

Posted by: Sharen Rumberger at March 29, 2009 11:09 PM

it's nice to see the drug companies can make all this money selling poison. if patients could buy antipychs, mdma, and heroin over the counter, which do you think they would choose? it's a shame this country as become so dumbed down in such a short period of time. and it's rather amazing too. it makes us understand how someone like hitler came to power; and how american can elect such poor leaders. maybe the so called "negative symptoms" are smart people who don't want to participate in a bullshit society.

Posted by: Alex at June 3, 2009 07:24 PM
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