October 09, 2008

Study: St. John's Wort As Effective As Prozac

A new British study has reportedly found that St. John's Wort is as good as Prozac at treating depression:

"'The herbal remedy St John’s wort can be as good at lifting depression as drugs like Prozac,' the Daily Express reported. It said that scientists had pooled data from 29 studies that compared the effect of the plant Hypericum perforatum to placebos and anti-depressants in treating people with depression. The Daily Mail said this was the most thorough study of the plant yet, and found it not only to be just as effective as Prozac, but to also have fewer side effects. However, cautions are made that some St John’s wort products are more effective than others."

I've not been able to locate the study yet, so I'll try to update this once I've seen the study.

I know that the effectiveness of St. John's Wort has long been controversial and that it's generally been found to be somewhat useful for mild depression but it's otherwise not a very robust treatment. That said, millions in Germany, where St. John's Wort is especially popular, take the treatment and find it to be effective. Maybe they know something we don't.

A 1998 study, led by one of the researchers of the new study, found more mixed results, but generally concluded that St. John's Wort was about as effective as anti-depressants in treating mild to moderate depression.

Posted by Philip Dawdy at October 9, 2008 12:03 AM
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Comments

Recently my son agreed to take some herbal supplements. He's now taking Omega3, St. John's Wort, and Ginkgo Biloba, and appears to be doing well.

He was not happy with the "flat" feeling that his previous meds left him with. Once he turned 18 he refused his prescribed meds; Wellbutrin, Abilify, and Seroquel.

Together we're trying to keep him feeling stable, but not "flat". I think it may be working. Keeping my fingers crossed.

Posted by: nvam at October 9, 2008 05:01 AM

you know, I don't doubt the results of this test but treating a single symptom with a single herb is really no different than taking a drug...not to say there is necessarily anything wrong with it, but to truly treat holistically and get to the source of the problem it's necessary to deal with the whole body and mins not just a symptom...just to throw out the idea to those who are interested in cure and a real paradigm shift from the sick bind we find ourselves in.

Using St. John's Wort alone without healing the body and mind on more profound levels is just like taking an SSRI---perhaps sans all the atrocious side effects and so if that is all you want go for it...

But if you want to go deeper and heal more profoundly you have to get away from using herbs/and/or nutrients in an allopathic fashion. This is still within the realms of allopathy while simply using a non-pharmaceutical...

Alternative/holistic medicine is about living and eating differently.

Just something to chew on.

Posted by: Gianna at October 9, 2008 07:23 AM

According to MedPage, the studies which gave those most positive results for St. John's Wort were all German. Maybe there is a bias in German research to favor St. John's Wort. I am curious what the non-German studies have to say.

Posted by: Tony at October 9, 2008 02:28 PM

yes but if SSRIs aren't any more effective than placebo, what precisely does this mean.

Posted by: bruce at October 11, 2008 12:08 AM

Even the NIMH have a page that states "There is some scientific evidence that St. John's wort is useful for treating mild to moderate depression."

I also like that it lists "side effects". You know those things that we get when we take a pill. Here is just the most common "side effects" from this "natural" cure:

The most common side effects of St. John's wort include dry mouth, dizziness, diarrhea, nausea, increased sensitivity to sunlight, and fatigue.


People have *gasp* died from taking this as well. Thsi is really no different than taking a pill. Still has side effects, someof which have been lethal. Is no different than just popping a pill with no other treatment. Not to mention the fact you have no idea of purity, strength and other factors that can vary from brand to brand and even from bottle to bottle in the same brand.

I really dont see it as any different than a pharma company other than they have even less restrictions on them.

Posted by: JD at October 11, 2008 12:19 AM

St. Johns Wort is not regulated by the FDA and can cause serious liver and kidney problems if taken for a long period of time. My sister passed away at the age of 37 from complications. She was diabetic and the doctor suggested she try SJW instead of Prozac for her depression. When the autopsy was done, it was concluded that she had toxic levels of SJW in her blood stream that the liver was not filtering right. She was affectively poisoned. Herbs are never good to take more then a few weeks at a time. Until the FDA fixes the CODEX for herbs, we have no way to regulate the levels of 'stuff' that is in the herbs. At least pharmaceuticals are regulated. Germany and other European countries have more regulation for the herbal treatments they offer. Just be careful. It also can have more counteraction with meds you are already on.

Posted by: Kriss at October 15, 2008 03:46 PM

I grow herbs, mainly culinary. I've sold my organic herbs wholesale and have learned quite a lot in my decades of gardening. I have respect for herbs as medicine and concern for the way people misuse them. I would never purchase any herbal medicine in a store, only grow my own and even then well, I really don't use them medicinally. I've thought of using my STW in tea but for some reason always held back.

My feeling is that a lot of herbal medicine is flat-out folklore, often born of desperation. What else am I to make of a plant called pleurisy root, used for lung ailments...because it has lung-shaped *leaves*??? Hey, if I were out living in the woods with no penicillin available I'd take a chance on it curing my pneumonia too. But I don't, so I don't.

BUT, some herbs (digitalis, SJW and others) DO have properties that one needs to respect the same as one needs to respect (and research) any other medicine. Let's face it, if an herb is strong enough to be effective in a positive way, then it's going to be strong enough to affect you in a negative way if you misuse it, don't understand it or buy it from someone who doesn't know what they're doing or is caving in to the pressures of commerce in their production methods.

Kriss, I'm really sorry for your loss.

Posted by: Sherry at October 16, 2008 06:39 AM

MAOI's interact w/ so many foods & other meds so people have to be very, very careful when taking them. And as others mentioned, there is zero regulation of the "natural" meds - nobody really knows what or how much they're getting. No thanks.

Posted by: Lisa at October 16, 2008 09:21 AM
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