October 06, 2008

Anti-Depressant Sexual Problems Affect As Many As 70 Percent

I think we all collectively knew that sexual problems caused by anti-depressants affected a much higher percentage of users than the pharma companies ever admitted to, but this is ridiculous. From the People's Pharmacy column:

"When Prozac-like drugs were first introduced, no one knew how common sexual side effects might be. Pre-market testing suggested that such complications were relatively rare. Now we know that sexual problems may actually range from 30 percent to 70 percent of patients.

"Drugs like Celexa, Effexor, Lexapro, Paxil, Prozac and Zoloft are prescribed for anxiety, bulimia, depression, chronic fatigue syndrome, hot flashes, obsessive-compulsive disorder, PMS and post-traumatic stress disorder.

"Many people report that such drugs can reduce libido, interfere with arousal, delay or block orgasm and cause erectile dysfunction. A recent article suggests that sexual side effects may sometimes persist indefinitely, even after the drugs are discontinued (The Open Psychology Journal, Vol. 1, Pages 42-50, 2008).

"There are no obvious antidotes for this problem, though some doctors have tried drugs like Viagra. An antidepressant such as bupropion is less likely to cause sexual dysfunction."

70 percent is a major wowie.

I wrote about the Open Psychology Journal article earlier here.

Posted by Philip Dawdy at October 6, 2008 12:05 AM
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Comments

This explains my entire adult life: I was on Effexor years before I ever became involved with anyone. Hearing that the side effects may be permanent is somewhat depressing, to put it mildly.

Posted by: bf at October 6, 2008 04:32 AM

As a former patient and young man who has been on exactly every SSRI drug, I find this deeply troubling. No one has to tell me about this particular effect. Every, and I repeat, every SSRI drug I took (which is all of them) completely obliterated my sex drive and caused sexual dysfunction. My Harvard-faculty psychiatrist did not believe me early on many years ago, because the profession hadn't admitted to itself yet this problem existed. The dysfunction always continued for several months past the time I stopped the drug, but I'm sure that had something to do with the protracted withdrawal reactions I often had.

And in light of this obscene news about Nemeroff, you have to wonder. Is someone at the complete height of recognition in his field who is getting paid well well over 2 million dollars by these companies going to give a shit-enough to study the side effects of these drugs they so vigorously deny? The answer is no. But I hope Nemeroff's descent into his own self-created pit of scientific and professional ruin will speed the process along.

You look at real medical specialties and you see comparatively little contoversy and general good results for patients, considering many factors. But this is a totally different story. At this point psychiatry has little credibility and while the more thoughtful practioners recognize most or all of what is wrong, they always want to preserve in a self-defeating way vestiges of the things that don't work because -- 'well, maybe we can have serious change in someone else's lifetime.'

Psychiatry suffers from an excess of unuseful information and a lack of science and it's patients suffer.

Posted by: JC at October 6, 2008 07:55 AM

Dearest Philip:

I guess this another one of those post I won't be getting excited, stimulated,, standing at attention, or winking at gopher holes over. And just when you start to think it is safe to cross the street as a bipolar too {laughing}. I'm sure the next bit of bad news streaming down the pipeline will be abnormal hair growth in unsightly places. Sure glad I stay far away from those pesky anti-depressants {smirk}.
Yours Truly,
Stan

Posted by: stan at October 6, 2008 12:34 PM

70 percent. Wow. I know I have had some trouble in the past when on different antidepressants. Prozac was the worst by far. I am now on Wellbutrin and have no trouble at all. I can also say that the troubles I had with other medicines all subsided when the med got out of my system.

Posted by: Matt Reeder at October 6, 2008 08:25 PM

Actually, Effexor not only raised my depressive "floor", making living each day worth while, but it has taken the neediness and anxiety out of my sexuality. Now for me, sex is a beautiful bonus, and not a soul-crusher when absent. So, for me at least, the side effect is a very welcome one!

Posted by: Blueshift at December 15, 2008 11:50 AM
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