May 14, 2008

Seroquel Approved As New Lithium, Depression Next

AstraZeneca announced today the FDA has approved Seroquel, its $4 billion year in sales atypical antipsychotic, as a maintenance treatment for bipolar disorder used in conjunction with either Lithium of valproic acid (aka Depakote). Getting the drug approved as a maintenance treatment is tantamount to the FDA declaring it the new Lithium, the longtime "gold standard" maintenance drug for bipolar disorder. I congratulate AZ on getting this nasty little drug approved in such a way that they can now market it as a "forever" treatment and cannot wait to see the new ads. It's a drug the company has been researching for literally every condition under the sun--anxiety, depression, public speaking phobia, you name it--and it's now cropping up on America's streets as a drug of abuse, either snorted or mainlined. Nice.

Ever nicer, one analyst interviewed by Bloomberg noted:

"'Seroquel is increasingly being rolled out for additional indications and may, in due course, become the go-to product for depressive disorders,' Charles Stanley analyst Jeremy Batstone-Carr said in an e-mail."

The go-to drug for depression? How about the stay-away-from drug for depression? Or the take-once-in-a-blue-moon drug for depression?

Anyhow, Seroquel is set for FDA approval as a standalone maintenance treatment for depression and anxiety and I expect it to sail through the FDA approval process despite the fact that this drug really knocks people out. Good to those of you who take or will take this drug.

Posted by Philip Dawdy at May 14, 2008 12:18 PM
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Comments

I've been searching Wikipedia to verify how the pharmaceutical industry is linked to the articles.
Gee! They are there and manipulate every single line written about drugs.
If you search Seroquel you'll see that the article is ghost-written. On the "discussion" page somebody asks if the article was written by AstraZeneca.
I care about Wikipedia for when we search the Web for any disease the first answer is Wikipedia.
Try any: depression; ADHD; panic attack; schizophrenia (this is the most "impartial" article I believe because there is not a expensive drug "designed" for treatment); bipolarity;...
all leads to Wikipedia.
The SSRI article has already some data about harms but Seroquel haven't.
A good source are the "discussions".
If you leave any remark against you will be called... Mr. Cruise, anti-psychiatrist, scientologist...:)
You will also be called ignorant, and will receive lots of "ad hominem" arguments.
The article on "anti-psychiatry" is a disaster( not for them, of course). The only reason why http://furiousseasons.com/ is not there is because they don't consider Blogs as a "reliable source".
:)
A man who was bravely giving good arguments in one of the discussions was told to "open a Blog because he had no evidence... blah, blah..."
Nobody reads discussions and the articles are obviously pro-Big Pharma.
I'm bringing it up because I believe that it's very important to make people see the way these drugs are promoted.
It's a hard job for the medias are totally involved.
Is Delta Burke still claiming that Effexor saved her life?
:)


Posted by: Ana at May 14, 2008 01:45 PM

Dearest Philip:

I'm back now after a long moving process and internet provider battle. I’m sure you missed me and stayed up at night crying Philip (laughing}.

As far as this transformation from antidepressants to atypical antipsychotics sounds to me like it is a no brainer and pure unadulterated genius. Thanks to seroquel I'm diabetic to add to bipolar disorder. If anyone thinks Big Pharma is thinking about helping those with depression through this magical medication treatment process, with a kind, caring, compassionate heart, and NOT THIER ALMIGHTY BOTTOM LINE $$$$$ with new uses for these drugs. They need to take seroquel in large doses, because they are far crazier than I {laughing}.


But then that's my personal opinion, which at this time has not been approved by the FDA {Smirk}. Good thing that the number crunchers over at AstraZeneca have analyzed the advertizing, legal cost, and settlement payouts into the price of these drugs, or they would only be making 2 or 3 billion a year in pure blood money profit off of them. I'm not even going to say seroquel isn't an effective horse tranquilizer. It definitely does its job with all those pesky little side effects we shouldn’t really worry or be concerned about (diabetes, cardiovascular risk, tardive dyskinesia, and so forth). Just what every patient expects, loves, and hopes for from their medications. I say let's just get congress to write a nice fat pork barrel bill, and place large quantities of these drugs in the drinking water supply and get it over with {laughing}. Geez, that would be suicidal and would get me locked away {befuddled look comes across Stan’s face}. I guess I better finish this post and go into hiding before the CIA genetically white coat wearing Penguins track me down and place me in five points {smirk}.

Yours Truly
Stan

Posted by: Stan at May 14, 2008 04:29 PM

The FDA just approved the off-label use the psychiatrists have been doing for years. I remember when it was ZYPREXA AS AN ADD ON TO DEPAKOTE.

You have to applaud the PR pimps on this one. Watch for Abilfy next.

Posted by: Stephany at May 14, 2008 06:03 PM

Holy sh*t!

Posted by: Lilly NC at May 14, 2008 10:07 PM

I don't see how the approval of Seroquel as an ADJUNCT to Lithium and Depakote is "tantamount to the FDA declaring it the new Lithium." Lithium and Depakote are standalone treatments. If Seroquel had been approved as a standalone treatment for bipolar disorder I could see your point, but thus far it hasn't.

Personally, the combination of Depakote and Seroquel has helped me more than anything (medication-wise, that is) thus far. Can Seroquel be misused or abused? Certainly. But it does have its place in the legitimate treatment of legitimate conditions.

Posted by: MacLeod at May 15, 2008 06:15 AM

Yes, I've heard of three people who have said they are on Seroquel as a sleep aid. Beats me why they tell them that and then also give them prescriptions for sleeping pills and bennies.

Posted by: noni at May 16, 2008 07:57 PM

"But then that's my personal opinion, which at this time has not been approved by the FDA."

Stan,
Be patient! They have too much information from all US to analyze.

:)

Posted by: Ana at May 17, 2008 02:41 AM
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