January 29, 2008

ADHD Studies Cast Doubt On ADHD Treatment

A series of studies in December's Journal of the American Academy of Child & Adolescent Psychiatry is suddenly getting some attention because it raises serious questions about how ADHD is treated in children and teens, how well treatment works, what really drives ADHD--and whether it makes sense to medicate kids at all. The studies are based upon a cohort of 188 Finnish teens--the research is led by a Brit and an American, the teens have been tracked for several years--considered to have probably or definite signs that the disorder will continue into adulthood.

What the studies--including a central piece of research--found was that for many youngsters diagnosed with ADHD the disorder ebbed away in their later teen years. I don't want to read too much into the studies yet since they are complicated even if their implications are fairly clear.

These studies have not gotten much press attention so far, aside from an article last week on Psych Central and a good article yesterday in the Los Angles Times. That's too bad, because their publication represents yet another brain shake for the world of psychiatry. I'll pinch from the LAT version, especially because one of the researchers said something quite remarkable.

"Researchers found it is the can't-sit-still kids -- the stereotype of the "ADHD generation" -- who are most likely to mature out of the disease. Among those with persistent ADHD, they also found, half have problems with cognitive skills that are key to success in adulthood, but half have no such deficits.

"And when researchers compare the findings from Finland to studies of Americans with ADHD, an even more intriguing discovery emerges: By the time they're in their late teens, those who receive drugs for attention problems seem to fare about the same as those who do not."

Basically, the kids who daydream more do worse in the long term versus kids who are a fidgety who do better in the long-term, regardless of their meds situation.

"'This begs the question: Are current treatments really leading to improved outcome over time?' wrote UCLA neuropsychologist Susan L. Smalley and co-author Dr. Marjo-Riitta Järvelin."

Sounds like the answer is no for a significant proportion of kids diagnosed with ADHD.

"In Finland, as in studies of U.S. populations, about half of older teens with persistent ADHD performed poorly on tests of short-term, or working memory, and in cognitive skills that are key to problem-solving, making plans and executing tasks. And in each group, roughly the same proportion of children 'mature out' of the disorder.

"Although about 60% of American children diagnosed with ADHD are medicated -- at least at some point -- for its symptoms, virtually no Finnish children are given medication. And yet, by the time they reach 16 to 18 years old, these two populations look very much the same.

"In an interview, Smalley stressed that the studies do not cast doubt on the short-term benefits a child with ADHD may get from a stimulant or other medication that treats the symptoms of the disorder. She cited recent studies showing that at the end of one year, children medicated for ADHD symptoms function better at home and school than those who get behavioral and cognitive therapy. But after three years, the difference between the two groups begins to wane."

Interestingly, the Finnish studies parallel conclusions from a set of American studies in November, showing that ADHD kids in the US do just fine over time. They also tie in with points Bruce Levine made yesterday about the pathologizing of teen defiance (sometimes diagnosed as ADHD).

I am beginning to think we are seeing a decent body of evidence supporting the idea that we've gone a bit too far as a culture--and I am talking Western civilization, not just the US--in diagnosing disorders in kids and teens and making them and their parents feel like fools for not getting the kids on meds. In other words, we need to be a bit more flexible in our cultural assumptions of how children should be allowed to behave and how we expect them to develop. It's time to let kids be kids--and in particular it is time we let boys be boys again, as most of the ADHD diagnosing and medicating in this country at least is among boys.

Happily for me at least, Smalley agrees with my basic argument:

"'We need to step back and embrace neurodiversity, diversity in human behavior and try to work on ways to embrace and enhance being at the extreme, instead of only focusing on the deficits and disorder aspects of ADHD,' Smalley said."

Yes, we do. And while we're at with regards to ADHD, there are some other disorders--alleged or otherwise--that deserve a thorough rethinking. But I won't go there today. But, as Psych Central noted last week, this does sort of demand a new approach to treating ADHD.

I'm sure that these studies will generate as much controversy as did the studies last November, now that they are getting slightly wider attention. Can a Judith Warner column be far off in the New York Times? I see another round of the so-called Ritalin Wars a-comin.'

The studies didn't take up any questions around the use of anti-psychotics in treating ADHD in boys, which seems to be enjoying a creepy vogue in the US. I've written about this before here.

I'll have more on these studies as soon as I've been able to review them in their entirety.

It's nice to see the LAT out in front on one of these stories for a change. In the past, the paper has been a strong voice (particularly on the editorial page) for the "medicate 'em and forget 'em" paradigm of mental health care and I have given the paper hell over this. Lately, the paper seems to be doing a better job, amazing considering all the cost cutting and personnel insanity that the paper's new owners (and its most recent previous owners, the Tribune Company) have been enforcing upon what's a pretty good shop.

Posted by Philip Dawdy at January 29, 2008 01:14 AM
StumbleUpon Toolbar del.icio.us Digg it reddit
Comments

Philip,

This is quite interesting to me for a very different reason to the one you note. It was JAACAP that published the infamous ghostwritten paper, fronted by Marty Keller, Neal Ryan, and our old mate Harold Koplewicz, et al, alleging the efficacy and safety of Paxil in minors. The Editor, Dr Mina Dulcan, came in for some quite stiff criticism on the ground that she appeared not to notice what a lot of old tosh she was printing, in spite of some of the reviewers' comments.

In comparison, a piece questioning the routine medicalization of childhood behaviours seems like something of a departure.

Matt

Posted by: Matthew Holford at January 29, 2008 05:32 PM

Oh, and the other incident that is called to mind, concerning, JAACAP is the Gilberg affair. Aubrey (Blumsohn) has several posts on this, but basically, there were allegations of falsification of evidence underpinning a paper that JAACAP published. The guy leading the research team then destroyed all his data (I think after he'd been ordered to make it available for scrutiny). JAACAP maintained a studied silence on the matter.

Matt

Posted by: Matthew Holford at January 30, 2008 02:00 AM
Post a comment









Remember personal info?






pic1.jpg

Winter Fundraiser Underway!!!
Patient Blogs. Sites.
Doctor Blogs. Sites.
Activists. News.
Social Networking. Forums.
Science. Big Pharma. Ethics.
Current Affairs
Seattle Stuff
Smoking. Stuff.

Info
About Furious Seasons
Email
Other Articles
ZYPREXA Documents
Alt ZYPREXA Documents Source
Blakemore-Brown Transcript

 Subscribe in a reader

Recent Entries
Winter Fundraiser, An Early Start
Reasons To Be Skeptical Of "Female Viagra" Drug, Big Pharma's Spanish Fly
Medical Marijuana For Autism?
AstraZeneca Whines About Chicago Tribune's Seroquel Coverage
Big Pharma's Sneaky Trick
Researchers Ignore Problems With Meds In Early Deaths, Blame Smoking, No Exercise
Researchers' New Pediatric Bipolar Disorder Symptoms Include Bed Wetting, Nightmares
Fort Hood Shooting: Was Psychiatrist-Shooter Psychotic Or A Terrorist?
Yale Researcher Links Childhood ADHD To Adult Crime, Drug Dealing
Senator Wants Pentagon To Account For Troop Anti-Depressant Use, Suicide Link
British Government To Limit Antipsychotic Use For Dementia
Child Psychiatrists Behaving Badly With Children
Utah Settles Zyprexa Claims For $24 Million
Psychiatrist Got $490,000 Pimping For Seroquel, Engaged In Wide Off-Label Use
Why Auto Insurance And Health Insurance Aren't The Same, Mr. President
Recent Comments

Matthew Holford on ADHD Studies Cast Doubt On ADHD Treatment

Matthew Holford on ADHD Studies Cast Doubt On ADHD Treatment

Archives
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
October 2006
September 2006
August 2006
July 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005
September 2005
Resources
Mental Health America
National Alliance on Mental Illness
Depression and Bipolar Support Alliance
National Institute of Mental Health
McMan Web
Search


Powered by
Movable Type 3.2