November 30, 2007

Hundreds Of Reports Of Suicide, Suicidality On Chantix

A reporter at a Dallas TV station did some good digging and requested data on complaints filed with the FDA related the stop-smoking drug Chantix. Here's what the FDA reported:

" After an initial report on Albrecht's death, News 8 requested, through the Freedom of Information Act, all the complaints filed with the FDA about Chantix. A computer disc was sent with 5,157 complaints, which were all filed in just one week after the News 8 report aired.

"Suicide was reported 55 times. Suicidal thoughts were mentioned in 199 cases and 417 people complained of depression."

I've had written about this drug numerous times now. It is a problem drug and the FDA is doing a safety review of Chantix, less than two years after it hit the market. That's lightning speed by FDA standards. I'm sure there will be much more to come on this story.

Chantix strikes me as being another Paxil. I wonder what the anti-smoking advocates make of this.

Posted by Philip Dawdy at November 30, 2007 12:05 AM
StumbleUpon Toolbar del.icio.us Digg it reddit
Comments

Surely there should be some serious risk assessment done by anyone prescribing this, as in which is more dangerous smoking or taking Chantix. I suppose in some rare cases Chantix might win out but for most people it looks like it's more dangersous than smoking imho.

Posted by: Sally at November 30, 2007 09:35 AM

It's amazing how the side effects of this drug are pretty smiliar to the psychotropics and the attention it gets, but we never hear about the side effects of the psychotropics. Psychiatrist must not be prescribing this one?

Posted by: Jane at November 30, 2007 09:11 PM

Smoking IS incredibly dangerous -- without doubt one of the leading causes of premature death and disability worldwide. The drug companies will beat this drum nonstop in support of Chantix.

What they'll try to sidestep is that there are LOTS of other ways to quit smoking: tapering off with nicotine gum or patches; hypnosis; behavioral techniques; even Wellbutrin. None of which are guaranteed but none of which have been proven to be inferior to Chantix.

I've got a friend who is doing quite well with Chantix; he especially likes their "support system" which consists of logging on to report your progress and getting e-mails of support. I'm glad my buddy's quitting cancer sticks, and apparently without ill effects. But I suspect the "e-support" is aimed mainly to retain patients who either don't need the stuff anymore or are bothered by the side effects. Clever, huh?

PS: the company is already pointing out that nicotine withdrawal is tough, and jonesing smokers have been known to go a bit crazy. I've known a lot of people to be irritable while quitting... but none who have beaten people up, or tried to kill themselves. Come on guys.

Posted by: Johanna at December 1, 2007 07:44 AM

There doesn't seem a lot of point taking the drug anyway, when Pfizer state:

“Quitting smoking, with or without treatment, is associated with nicotine withdrawal symptoms and has also been associated with the exacerbation of underlying psychiatric illness.”

Isn't that supposed to be the point of the drug, to "scientifically" (using the term very loosely) reduce the cravings?

If suicides takes place on the drug in perfectly normal individuals that have never had any sign of mental disturbance, then

a) the drug doesn't actually work as they claim with regard to reducing cravings, ergo its a waste of money at the very least, or

b) it causes suicidal ideation (just like it says on the label of its can of rxlist side effects).

A bit of a dilemna for Pfizer - they could pick one and get away with it: A, their drug doesn't do what it says, or B, it does, but suicidal ideation is ONE of the life threatening adverse effects?

They can't hope to get away for long with saying withdrawal brings out underlying mental illness when there's never been any sign of one, that would clearly be trying to blaming those 'invisible faries at the bottom of the garden' and even the most naive people totally unaware of the rampant scienfic fraud that goes on aren't THAT stupid.

The above Pfizer statement can be found in this article (dated 30th November 07)
http://www.thesun.co.uk/sol/homepage/news/article527476.ece
regarding a "happy go lucky" man, excited about giving up and with absolutely no history of mental disorders, depression or moodiness, committed suicide after 1 month on Champix (as its called in the UK) and only a few days after he'd booked a holiday to Cuba.

The ADR reports allegedly received by the MHRA - the UK's version of the FDA and just about as...reliable and trustworthy (!) - are stated in an article here:
http://news.bbc.co.uk/1/hi/health/7115696.stm

With regard to smoking, because I doubted something I'd read about Japan and smoking on a recent article about the UK suicide, I checked it out. Its rather interesting! Worth a read.

Here first:

http://forums.about.com/n/pfx/forum.aspx?msg=732.1&nav=messages&webtag=ab-seniorhealth


and then to verify the situation, here:http://www.oecd.org/dataoecd/45/51/38979974.pdf


Posted by: pg at December 1, 2007 11:48 AM

I have been reading these reports on suicide and chantix and thought I'd add my two cents for what it's worth. My husband was a two to two and a half pack a day smoker for over 35 years. He smoked heavilly and sometimes chain smoked. He had tried to quit at least ten times before. Patches, gum, lozenges, and cold turkey. Nothing worked. He was irritable, cranky, nasty and his temper raging every time he tried to quit, to the point, I almost want to say I welcomed his smoking again. On Sept 14th, 2007 he started Chantix. He absolutely loved the medication. The only minor side effect that he and I noticed was some loss of libido. He did have vivid dreams, nothing violent though as some have reported. He basically had dreams about old friends and places where he'd worked in the past. He had planned on taking it for the full three months, and our doctor actually wanted him to take it for 6 months since he was such a heavy smoker. He forgot to take it a few times after dinner and didn't have any cravings that he couldn't handle, so decided to stop taking the drug after using it after 72 days. He is still not smoking, and I am confident he never will again. He only has great things to say about the drug and said, he'd still be smoking if he hadnt taken it. He especially loved the support on the web site, especially where it told him everyday how much money he had saved to that point. He has nothing but good things to say about the drug. I am thankful he didn't suffer any side effects, and am absolutely thankful I can now call him a non smoker.
Barb

Posted by: Barbara at December 7, 2007 03:53 PM

well I would like to comment on chantix I took it for 80 days and I got so depressed and very suicidal. Basically I went crazy. I totally lost it in front of my parents and im 43 years old i have a daughter and i didnt want to live anymore.It scared me so much and I couldnt figure out why i was acting so depressed and had all these horrible taughts in my head. I never had any of those vivid dreams just got really depressed. So I quit taking chantix and it took while for me to feel back like myself. I work with the public and i have so many people ask me about the pill and tell them not to take it because it turned me crazy and very suicidal I just thought i would let you all know how it affected me

Posted by: denise at January 23, 2008 05:37 PM
Post a comment









Remember personal info?






pic1.jpg

Patient Blogs. Sites.
Doctor Blogs. Sites.
Activists. News.
Social Networking. Forums.
Science. Big Pharma. Ethics.
Current Affairs
Seattle Stuff
Smoking. Stuff.

Info
About Furious Seasons
Email
Other Articles
ZYPREXA Documents
Alt ZYPREXA Documents Source
Blakemore-Brown Transcript

 Subscribe in a reader

Recent Entries
Jim Carrey Criticizes Extended Anti-Depressant Use
FDA Orders Suicide Warning For Bipolar, Epilepsy Drugs
Another Seroquel Related Arrest
Minnesota Forced ECT Case Hits NPR Airwaves
Fundraiser Over
Boston Globe Reports Sexual Problems With SSRIs As High As 50 Percent
Winter Fundraiser, So Close It's Not Even Funny
Two Child Physicians Criticize ADHD Meds, The Bipolar Child, Pharma Influence
Michael Phelps: "I Didn't Want To Take Ritalin Anymore"
Winter Fundraiser, Oh So Close
Winter Fundraiser, Inching Closer
10-Year-Old Who Killed Father After Beginning Prozac Gets New Trial
Scientific American Interview: Is Depression Overdiagnosed?
Winter Fundraiser, Day 11
Paxil Documents Online
Recent Comments

denise on Hundreds Of Reports Of Suicide, Suicidality On Chantix

Barbara on Hundreds Of Reports Of Suicide, Suicidality On Chantix

pg on Hundreds Of Reports Of Suicide, Suicidality On Chantix

Johanna on Hundreds Of Reports Of Suicide, Suicidality On Chantix

Jane on Hundreds Of Reports Of Suicide, Suicidality On Chantix

Sally on Hundreds Of Reports Of Suicide, Suicidality On Chantix

Archives
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
October 2006
September 2006
August 2006
July 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005
September 2005
Resources
Mental Health America
National Alliance on Mental Illness
Depression and Bipolar Support Alliance
National Institute of Mental Health
McMan Web
Search


Powered by
Movable Type 3.2