October 31, 2007Lithium Increases Lifespans?Thats a claim being made by researchers at the Buck Institute. A press release states: "Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication." That kind of makes me wonder if nematodes--c. elegans in formal parlance--have anything resembling kidneys in their simple bodies. God knows, long term Lithium use isn't especially friendly to human kidneys. Does anyone know what the scientific evidence is--or isn't--on how Lithium affects lifespans in humans? All the same, an interesting and suggestive study. Perhaps, the researchers will next try some Zyprexa on those little worms. Anyone want to bet we don't end up seeing an "Olanzapine extends life" press release as a result? Posted by Philip Dawdy at October 31, 2007 12:01 AM
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Great, I may have kidney failure from lithium, but nobody thinks I look my age. Hmm, look younger and die younger or look older and die older, which sounds better? :) Posted by: Alison Hymes at October 31, 2007 07:01 AMWill not be a guinea pig only to die on Zyprexa. But I'll let you know on the lithium, being 66 and taking it for a few years. I wonder if there is a study and if it factored in only longevity or length of time on the drug. If I live to be 100, still taking lithium, Pharma may want to make a copycat drug and re-patent it. Posted by: Ghost at October 31, 2007 07:36 AMWith or without lithium the mental health system has done a miserable job of helping those who have received services remain alive. An average of 32 years of potential life lost ........ In the putative era of "Wellness & Recovery" too many aren't living long enough to achieve either. http://psychservices.psychiatryonline.org/cgi/content/full/57/10/1482 Posted by: Joe at October 31, 2007 07:42 AMWell you said it before I could. The first thing I thought when I was the title to your post was is that how I know two people who died of kidney failure due to lithium poisoning---one in their 40's and one in their 50's? Lithium is very toxic. This is an interview with Dr.Manji on the CABF[Child and Adolescent Bipolar Foundation]site. Discussing Bipolar and Lithium's beneficial properties. Interview with Husseini, Manji M.D.. "Speaking of lithium, your research has uncovered some of its intriguing beneficial properties. Can you highlight the most important ones?" Manji: "We did MRI scans and MRS spectroscopy and then put them on lithium in a blinded fashion for 4-6 weeks. Then we did the scans again. We found that almost every single person taking lithium had an increase in N-acetylaspartic acid (NAA) [an amino acid that is viewed as a marker of neuronal health]. And the actual amount of gray matter was going up when they were treated chronically with lithium." Considering that lithium has been used for the past fifty years or so to treat depression, if it does prolong lifespan, we should soon see the results in the human population. And then what will we prescribe? Posted by: Laowaitattler at October 31, 2007 12:15 PMGreat. I am on 2,500 mg right now. I can't wait for the blood work to be done tomorrow and find out my levels are too high. As for the Nematodes, wasn't there a time in history where people thought leeches were awesome and the cure for everything?
I know that when I'm depressed I sure as hell don't want some doctor prescribing me something that is going to make my life longer. Especially if I'm going to still be depressed taking the f@$King drug! Posted by: Jane at November 1, 2007 06:53 PMI know that when I'm depressed I sure as hell don't want some doctor prescribing me something that is going to make my life longer. Especially if I'm going to still be depressed taking the f@$King drug! Posted by: Jane at November 1, 2007 06:53 PMPost a comment
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