Most psych meds are processed via the liver, and many patients do not realize that they are/can be hypersensitive to any medication/cough syrups/etc. that are processed through Cytochrome P450 2D6 (CYP2D6).

If a person gets genetic testing done, it is easy to find out what medications can react positively or negatively, ultimately giving doctors an edge on prescribing medications that will work for the patient without a lot of trial and error. I feel it is an area not many people have researched, and there are labs that do these blood work ups. IF insurance companies required that for all patients, it would cut costs for all involved, by the trial and error method we currently have for psychiatric medications.

CYP2D6

If consumers/patients did more research themselves, it isn't hard to figure out what med categories work for them, and why they don't.

The medications processed via the liver, are often the ones that give patients the most problems mentally.[as in they don't work, and often cause more harm than good.]

Aside from this liver stuff, I'd like to take out my soapbox, stand on it, and state that Cymbalta is a pile of crap for other reasons...namely the fact that withdrawing from it can make you want to kill yourself. That's pretty much what I almost did at the end of 2005, and it goes right in line with what happened during the illustrious clinical trials of the drug as well. This medication is crap and should not be offered to ANYONE.