May 11, 2007

We Are All Bipolar Now, Or The Norming Of America

As I noted on Tuesday, a new study claims that 4.5 percent of the American population has bipolar disorder. Bipolar disorder in this study is understood as BP-I, BP-2 and subthreshold bipolar disorder. SBD, as I am calling it, doesn't exist in the DSM. Until recently, prevalence studies estimated bipolar disorder at about 1 percent of the adult population. NIMH bumped its estimate last year to a bit over 2 percent (which seems about right). Meanwhile, pharma companies and some researchers said it was 5 percent and I read one journal article where a researcher pegged it at 11 percent.

My reading of this is that much of that increase is linked to an expanded definition of bipolar disorder as a spectrum disorder (spectrum disorders are all the rage these days) with SBD being the catch basin for all the soft bipolar researchers claim they are detecting in America these days. And so begins the war on the weird, the productive and the agitated of America.

If this strikes you as unimportant, perhaps you don't understand how all the dots connect around bipolar disorder the last few years. Zyprexa, Rebecca Riley, the bipolar child controversy, Seroquel declared the bipolar pill, class action lawsuits, multi-billion dollar settlements, researchers cooking research, black box warnings, calls for more outpatient commitment and so on. All of those bits connect with bipolar disorder in our culture and are evidence of the weaknesses--and dangers--of current treatment paradigms for bipolar disorder. And yet we have researchers, one cabinet level department (HHS), two private foundations and many pharmaceutical companies who would like to double or triple the number of Americans who must be convinced they have bipolar disorder, be instructed that it is a lifetime illness and be pressured to take medications that have a less than 50 percent chance of doing much for you and anywhere from a 30 percent to 50 percent chance of causing you an injury (I'm done with sugar coating it by calling injuries "side effects"). Forget about the usual criticism that this is all a naked land grab by pharma companies and researchers looking to line their pockets.

It's darker than that. What we've got going on here is the norming of America--a big happy party wherein Americans are forced to have their behaviors, thoughts, impulses and expressions grouped around a carefully-controlled norm. That norm is being created--has already been created some would argue--by leading researchers such as the bipolar mafia (adult division) at Harvard and the fine folks at NIMH. Any day, I expect a study proclaiming doctors as the new behavioral norms for American society. No, I am not joking.

To take this new SBD "diagnosis" at face value, then anyone who's experienced a period of insomnia and been more productive than usual at the same time has bipolar disorder. People like artists, entrepreneurs, writers, musicians, Presidents, soldiers, grad students and 4 a.m. poets have bipolar disorder--or are at risk of succumbing to its symptoms!--and must be medicated. Tom Waits, put down that whisky bottle and Marlboros and pick up the Seroquel. We are norming you! Same goes for you, Keith Richards. (CL Psych does a much better job here of poking through the SBD diagnosis. Read it.) I am really surprised that the authors didn't insist upon horniness as an SBD symptom.

I am so not interested in living in this normed world--the one without weirdness of any kind. Because it's all been dopamined to death. And a level flat world is no place I want to live. It will be odorless, tasteless, smooth and uninspiring in the extreme. Kinda like the back wards in "Brave New World."

The press has entirely missed just how important and off-base this study is. Yetserday, the study's lead author, Kathleen Merikangas an epidemiologist
from NIMH, spoke to Reuters in an article titled "Severe impairment common in bipolar disorder:"

"Regardless of the classification, the evidence suggests that impairment is often severe and few patients with bipolar disorder receive appropriate treatment....

"'One criticism we always get is that we're 'medicalizing' everything' and artificially inflating prevalence rates, Merikangas said, instead of recognizing symptoms as 'the normal ups and downs of life.' However, bipolar disorder, including subthreshold bipolar disorder, 'really does impair people,' she stated.

"Study results verify the clinical severity of the disorder, the team maintains, as reflected by the number of episodes, chronicity, symptom severity, impairment and the presence of other illnesses. The observation of increasing symptom severity from one category to the next reinforces 'the validity of the spectrum concept of bipolarity,' the researchers note."

The article doesn't even establish what this vague impairment of SBD might be much less BP-II. Nor does the journal article itself although it lays out something called "role impairment" (yes, we must all conform to our assigned roles in life or we are impaired). In the journal article the authors insist that "Subthreshold BPD is common, clinically significant and undetected in treatment settings."

Most media articles have spoken of only half of all bipolar cases being detected as their news hook. That's laziness. You cannot create a DSM diagnosis out of thin air and then say it's the same thing as the already existing DX and use that as a basis to claim that the problem is twice as bad as it was before. Why some reporters out there are not asking skeptical questions about all the inherent assumptions being made in that kind of thinking is beyond me. Except reporters are trained to always respect doctors--wow, they went to medical school!--and not to question what they say except to spell the Greco-Roman disease names properly. Maybe they are impaired.

Anyhow, I simply love that NIMH's press release on the study appears on the Medical News Today site on a page that features a vague ad about how your depression could really be bipolar disorder. Click on the link and up comes a Seroquel ad where you can take a self-assessment test.

I could go on about this all night, but my back is telling me that I mustn't. Beyond what I see as the darker--and dumber--implications of such research and the press' coverage of the same, it distresses me as an old school manic depressive (back before we got the politically correct bipolar disorder and BP-II) that instead of finding long-promised "cures" for behavioral problems in American society and instead of hammering out efficacious psychological therapies, we now have a medical model of mental illness that is far more interested in finding more patients for a paradigm of diagnosis and treatment that are weak in their conception and weaker in their technology. That's not good. Because soon any agitated, impulsive person who's never had a manic moment in their lives won't have to offer an accounting for their behaviors to themselves or to anyone else.

They'll just say, "Oh, I'm SBD."

Posted by Philip Dawdy at May 11, 2007 12:48 AM
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Comments

Right on! I agree 100%. You should add in the new Bipolar 3. Supposedly, no SSRI/SSNRIs for them, but atypicals seem to work :)

As in any good business model, the atypical makers will not meet their goals for 2010 unless they have an increase in rate of "serious disorders" among the groups "so hard to bring in", such as whistle blowers (cause distress to others), animals (big NEW market potential), reptiles (full of negative symptoms), teenagers (we KNOW they are crazy), the elderly (sad, lonely?), pregnant women (very moody), those under 1 year old (i actually heard this talk, Phillip) AND of course, anyone, who is experiencing human tragedy or drama, and are distressed or in adjustment disorder (myself).
I have even heard talk of indications for those with more than 4 serious life events in a short time. This just blows.
With all these NEW indications, they can then meet their shareholder's intrinsic expectations for growth. I wish you freedom from pain in the near future.

Love and Peace,

BK

Posted by: Dr. Black Kitty at May 11, 2007 05:42 AM

This is really excellent commentary and thank you for making it. The only thing I'd like to add is that in addition to stretching the diagnosis to include a whole lot of decent creative folks who get a buzz of extra energy from time to time there's something even more insidious going on and that is, drug-induced mania and bipolar disorder. First the industry "sells" depression (easy to do) and gets a whole lot of people on antidepressants and then a certain percentage of them become manic, even psychotic, as a RESULT of the drug, and this opens up a whole new market for even stronger drugs. This is definitely part of what's going on -- manufacturing the sickness in a number of different ways. It's great for business.

Posted by: Sara at May 11, 2007 06:19 AM

thank you Philip! I'm linking to this from my blog. I've been wanting to write something of this nature, but have not been well. I'm so glad you did it for me (and much better then I would've done it anyway!)

Posted by: Gianna at May 11, 2007 07:32 AM

This is a great post.

It makes me think about how in the "old days" people were classified as good ol' Type A personalities, hot heads, or eccentric creative artists, etc. Now we are manic, O.D.D., O.C.D, M.D.D and hypersexual; all symtomatic of the new SBD spectrum, and officially being slammed down on hardcore chemicals.
The world without music, art, literature, theatre, or fights on a baseball field or hockey game---can we imagine such a place?
My psych asked me if I drank wine with dinner as a way to self-medicate. I told him I liked wine with cheese, and as far as classifying it as self-medicating--what's worse? that --or the all day stupor Seroquel was leaving me in, unable to function--and basically legally bombed.

This Pharma attack on society is unbelievable. We will be a changed country. Once everyone is on a medication of some sort---and more are than admit---we will most likely never see another Van Gogh or Pete Rose come out of the crowd.

Posted by: Stephany at May 11, 2007 07:45 AM

Just wanted to note that BP-III is "created" from taking antidepressants.


and...

http://www.psychiatrictimes.com/psychiatryNews/showArticle.jhtml?articleID=199400206&cid=BreakingNews


The criteria for subthreshold bipolar disorder were:
Recurrent subthreshold hypomania (at least two criterion B symptoms and all other criteria for hypomania) in the presence of major depression.

At least two episodes of hypomania in the absence of recurrent major depression.

Recurrent subthreshold hypomania in the absence of major depression.

Sounds like just someone who has been happy once or twice in his/her life.

Posted by: christin at May 11, 2007 09:26 AM

Hi Phillip,

Hmmmmmm . . . I have mixed feelings about this posting. I have just been diagnosed as bipolar and I have just been prescribed Seroquel. A twofer. Frankly I don't know what to think.

For the past several years, I have been on a cycle with antidepressants where they work for a while and then diminish. I work my way to the upper end of the dosage level and when that stops working I get changed to another. I've burned through Prozac, Paxil, Effexor, Lexapro, and now Wellbutrin. It was after my latest response to the increase in Wellbutrin, shooting my anxiety levels through the roof and causing my moods to change directions faster than a fighter jet in an air show, that my doctor decided that I may be suffering from something other than chronic depression and GAD. Thus the Seroquel. At this point I don't care about the label; I just want my brain back.

For the past week I've been reading everything I can find on the net about living with bipolar disorder. That is how I found this blog. For that I would like to offer a "Thank You" for the information you provide.

Posted by: Craig at May 11, 2007 03:35 PM

They'll just say, "Oh, I'm SBD."

In general, people always have an excuse for their behavior. It was alcohol, it was drugs, it was the stress, people are mean, people don't understand, it was physical pain, my mother/father/wife/husband/partner/God didn't love me enough. And then there are the multitude of psych dxs and people using those dxs as excuses even tho they have not been diagnosed as such. I hear all the time from people how they're a little OCD or a little manic.


The majority of people want to take a pill to feel better. Psychotherapy of some flavor works about as well (at least from the studies I've seen), but it takes time and it takes energy and it will involve looking at the bad bits of your life. People in general don't want to change their diet or exercise more if it would mean that they would feel better. Taking a pill is easier and plus adverse side-effects give you something else to blame/use as an excuse. Because that's what people do. A lot of people get mad because they want a better pill. Really, we all just want a cure. We don't want unruly kids and we don't want to feel sad and we don't want to be a lot of things. We want to change and we want to embrace easy pre-packaged solutions (see current Oprah fad).


I am so not interested in living in this normed world--the one without weirdness of any kind.

And what about those who are weird but don't want to have to deal with despair? A lot of weird folks who fall within the bipolar spectrum do medicate themselves, with drugs/alcohol/sex/codependence. Which is the better approach; psych meds or the others? All of the above will fuck you up if you're not in control of how you are medicating yourself. Then again, it's hard to have control when you're crazy.


A diagnosis is a label. A category used to bucket together like observations of behaviors. Everyone is looking for some demarcation in psychiatry. Yes you are crazy or no you are not. Human being are just unique enough so that will probably never happen. A million things make us who we are (genetics, environmental, biological, etc.) and maybe a spectrum approach to mental illness will be the correct paradigm. Maybe 4% of the population is bipolar. Maybe we should only worry about it if you are BPD I or when someone needs help. That's pretty arbitrary too. I've had 5 or 6 dxs in my time.


I wonder if SBD is really going to cause all that many more psychiatric dxs. How many people go a dr (psych or gp) and complain of emotional issues and don't get prescribed and rx? How many people then defer on treatment until they have more info? How many get a second opinion? So now people will be told they have SBD instead of depression. Is there really a difference?

Posted by: Chloe at May 11, 2007 03:59 PM

This could backfire. Letting 5 or more percent of the population in on the dirty little secret that there is no "bipolar specific medication" only cast-off crap that does nothing more than produce side effects could be a bad thing for them in the long run.
*gasp* they may have to resort to actual research and development.
On a lighter note (or not)this is not as funny now, my pdoc and I actually joked about "what next, BP-IX for people who are a little down a couple of times a year and get excited at Christmas?"

Posted by: d at May 11, 2007 10:18 PM

@Craig

You said "I just want my brain back." I have to honestly say that you may not get it back following the "throw stuff at the wall and see what sticks" approach to prescriptions.

For example, I just saw my doctor for a problem with excess mucus. Yeah, pretty gross, tell me all about it. Nobody has been able to help me. None of the specialists, and not this doctor. He told me that I was out of his realm and that perhaps I should see another bunch of specialists over at the University of Utah. Then he gave me a bag full of Nexium samples because maybe I was having acid reflux problems which could cause hyper mucus production. I wasn't complaining about acid reflux, but there I was with a shiny, new bag of meds.

Doctors are too casual in their willingness to experiment with their patients' minds. You need to be proactive and less trusting. I'm with Philip on this one. "Side-effects" is too kind a word. I was treated for ADHD and Depression with Desoxyn and Zoloft and became neurologically damaged after only three weeks on the drugs. Which one did the damage? Both have been linked to inducing chronic motor tic disorder. Now I have it for life. I was better off before treatment.

I, too, used to move from antidepressant to antidepressant. Each med lost its efficacy rather quickly for me. The dosages went up, the side-effects went up. I gave it all up and worked on my own theories of thinking positive and forcing myself to be optimistic instead. Much better results. I now know that what I did was discover Cognitive Behavior Therapy on my own. I saw a CBT for a while and it was very helpful. I highly recommend it. Try to see one who can help you with medications as well. He'll want you to become more independent and will help you ween yourself off of them over time, but until you learn how to change your thinking patterns it will help to have them as a crutch, assuming they aren't damaging you. If they are damaging you get off them immediately. You might want to at least consider getting a second opinion before letting your current doctor use you like a lab beaker. And I hope you'll take my intensity for what it is - one depressive trying to help out another depressive before he is damaged by meds. I live with Depression but I can control it. It will take time but I'm willing to bet that you can learn to control it, too.

Philip, excellent article. Thanks for posting it.

~Douglas
-=-
The Splintered Mind - Overcoming Neurological Disabilities With Lots Of Humor And Attitude

Posted by: D Cootey at May 12, 2007 12:17 AM

I think this posting has generated a very interesting discussion. Thank you again, Phillip.

I would like to keep harping on my belief that people who have the tendency to hypomanic, should be very careful what drugs they take, even if they are prescribed.

I think that if a drug like Wellbutrin, makes you anxious, then they usually give you a benzo. Then if you get sleepy they give you aderall; then if you still feel racey they recommend Seroquel....

My impression is that primary care MDs DO NOT want to deal with psychiatric problems, so they try to push drugs which makes the MDs feel better, but not the patient.

I asked 3 MD psychiatrists if I should taper Neurotin (gabapentin) or could I quit cold turkey. They all said just stop. I was sick as a dog from doing that rapid tapering.

Thanks again.

Posted by: Dr. Black Kitty at May 13, 2007 03:18 AM

---I asked 3 MD psychiatrists if I should taper Neurotin (gabapentin) or could I quit cold turkey. They all said just stop. I was sick as a dog from doing that rapid tapering.---


Not to mention it's an anticonvulsant, and therefore stopping cold-turkey is a good way to court seizures.

Too many MDs are trying to be psychiatrists and the flooding of our society with this new diagnonsense doesn't make it any easier.

Yes, many are all too willing to assign a pill to whatever problem you come in with, whether they are actually qualified to or not.

The poor fellow with the mucus problem had a doctor simultaneously telling him he was NOT qualified and yet giving him medications anyway.

And now we are doubling the "afflicted".
Oh we got trouble.

Posted by: RabbitGirl at June 2, 2007 04:28 PM

VJt6th First of all, there�s no one else like YOU�your story is unique and you can tell about people, times, and places that only YOU can share.

Why not tell your grandchildren about you�.plus their grandparents, great-grandparents, and even their great-great grandparents (that�s

your grandparents)! It�s really about creating a loving, lasting bond�preserving not just life stories, but relationships, for

generations to come.

Of course, you can also give them your own advice about love, work, and how to lead a good life. Here was my grandma�s advice to me: �Be

what you want. If you do something, do it the best you can.� Because it�s my grandma, it means so much more. I�ll always be able to

remember what she said because it was actually written down. What�s your advice for your family? This is your opportunity to write it

down.

Reminiscing is good for you too! Over 100 studies over the last 10 years have found that reminiscing lowers depression, alleviates

physical symptoms (arthritis, asthma), and stimulates the hippocampus where memories are stored in the brain. So consider the great

health reasons for reminiscing too.

Posted by: Beth Sanders at July 18, 2007 09:22 AM

iUuuCE First there is the need to find the real meaning life has for you. This journey we are all on is a varied one, for sure, but there are some similar things we are all going through.

Each of us, in our search for meaning in life, has a vast amount of experience to draw upon. Our struggles and hardship, along with our achievements and blessings, teach us life’s lessons. Your experience, your strength and the hope that endures are part of your unique story — and part of the reason why you should tell your life story.

The second primary reason to tell your life story is to leave your mark. We all want to be remembered. Certainly we want to be remembered for the good we've done and for the significant accomplishments in our lives. There is satisfaction in a life well-lived. Living a life fully... richly experiencing what it means to be alive and involved in helping others is a great thing. To share with others who you are, what you are about and what you believe in is passing on some very valuable personal history.

Posted by: Maria Sanches at July 18, 2007 04:23 PM
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