January 15, 2007

Cymbalta In All-Caps

A comment came in over the weekend, concerning one person's recent experience with Cymbalta, a newish anti-depressant made by Eli Lilly. I thought it was worth posting on the main page and I'll leave it in its original all-caps form:

"I HAVE BEEN TAKING CYMBALTA FOR A LITTLE OVER A WEEK NOW, AND AFTER THE SICK TO MY STOMACH FADED, I HAVE BEEN GETTING MORE AND MORE DEPRESSED- I DON'T EVEN HAVE DEPRESSION! I HAVE REALLY BAD ANXIETY- WHICH THIS MED DID HELP WITH, BUT WHEN YOU CAN'T GET OUT OF BED IN THE MORNING OR THE AFTERNOON, IT'S REAL EASY NOT TO BE ANXIOUS. I HAVE BEEN IN BED AGAIN ALL DAY TODAY CRYING- FOR NO REASON, AND I JUST CAME ON THE COMPUTER TO SEE IT OTHERS FELT THIS WAY, AND I AM SO CONVINCED AFTER READING EVERYONE'S THOUGHTS, THAT AS OF RIGHT NOW I QUIT THIS DANGEROUS DRUG AND AM GOING BACK ON WELLBUTRIN."

Interesting, especially since it's in response to a 7-month-old post on the drug. As I have noted before, that should tell you something. Cymbalta was expected to hit about $1 billion in sales in 2006, its second full year of approval in treating depression, making it a major anti-depressant in the marketplace. What concerns me is that I have heard nothing but bad things from readers about this drug. If anyone has good experiences to report about Cymbalta, I'd like to hear them.

Until then, I am beginning to wonder if we don't have another Prozac or Paxil situation on our hands.

Posted by Philip Dawdy at January 15, 2007 04:08 AM
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Comments

Since we're sharing anecdotal evidence, I'll share mine. I've been taking Cymbalta for about six weeks now. It's the only thing that's made a dent in my anxiety. Over the past two years I've tried Wellbutrin, which gave me panic attacks, Zoloft, Buspar, and Lexapro. Nothing helped except Cymbalta. I've had no side effects from it and I feel like myself again.

Posted by: Jennifer at January 15, 2007 08:04 AM

Duloxetine (Cymbalta) is pretty much fluoxetine (Prozac) without the fluoride. But like bupropion (Wellbutrin), duloxetine effects noradreline and dopamine, like an amphetamine (methyl based).

Cymbalta is not really a novel drug, just an almagation other neurotransmitters reuptake inhibitors that were already on the market.

Posted by: Zip at January 15, 2007 11:11 AM

I have a family member taking this. I mentioned there was information out there that she might want to check out about the drug to be informed. She shrugged and said, "Is any drug perfect? I've heard that about Paxil and Prozac too...whatever." I suppose ignorance is bliss.

Posted by: Priscilla at January 15, 2007 12:26 PM

Cymbalta can cause liver toxicity--at this point they're only warning people with liver disease not to take it.

http://www.fda.gov/medwatch/safety/2005/safety05.htm#Cymbalta

Posted by: W at January 18, 2007 11:35 PM

Cymbalta has saved my life. Enough said.

Posted by: John Kwon at January 24, 2007 11:29 AM

I've been on Cymbalta for over a year. It's been effective and the only side effect I've had is an increased tendency to bruise. I've had good experiences with both Zoloft and Wellbutrin, both both stopped working after a while. No luck with Serzone, Effexor, Elavil, Sinequan, and many others.

Posted by: zasu pitts at January 24, 2007 05:40 PM

My Dr. started me on Cymbalta 1 week ago. He said I would feel funny after taking them ,well I was crying so much that I forgot to ask (what he meant by that,,funny ,,like how) he is on vacation so I will ask him next week. Was anyone else told of some sort of different feelings during the first week of taking this med?Thanks for info!
Linda

Posted by: Linda at February 18, 2007 08:17 AM

DO YOU THINK THIS IS A DANGEROUS MEDICATION TO BE TAKEN..THANKS BECKH

Posted by: BECKYGANN at March 18, 2007 03:24 AM

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