December 21, 2006

The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Just as I thought I was going to drift off for a few days, the New York Times has yet another revelation:

"The original results showed that patients on Zyprexa, Lilly’s pill for schizophrenia, were 3.5 times as likely to experience high blood sugar levels as those taking a placebo, according to a February 2000 memo sent to top Lilly scientists....But the results that Lilly eventually provided to doctors until at least late 2001 were very different. Those results indicated that patients taking Zyprexa were only slightly more likely to suffer high blood sugar as those taking a placebo, or an inactive pill."

How many more legs does this story have? It's now obvious why the court ordered the Alaska lawyer to return the documents from the Zyprexa class-action suit to the loving arms of court seal: it's simply not good for the American people to know a major corporation's dirty secrets, regardless of whatever health problems they might create.

More to come, I am sure.

Posted by Philip Dawdy at December 21, 2006 12:05 AM
StumbleUpon Toolbar del.icio.us Digg it reddit
Comments

Can I just tell you how much I love you? (not in that creepy stalker way) No, really, I love this coverage - it's absolutely fascinating. And I appreciate your stellar (blogging) coverage on this.

Good job - enjoy your day (or two) off and I look forward to future posts.

Posted by: Marissa Miller at December 21, 2006 06:15 AM

Okay. I am so disgusted beyond what I already was before re: ZyPrexa, that I will try and make this my last rant about it.

In 2003, my daughter had blood sugar variations through-out the day so many times, that it was written into her (legal document)I.E.P. in high school, that she needed protein bars and water any time of the day, in any class, and would not be penalized for leaving class due to any symtoms regarding this need. Keep in mind, that creating, and gaining an IEP for accomodations in schools, is not easy, and for a detail like that to get into the document back then was a victory. (and now think about how unnecessary).
I took her to the doc, and she was not officially deemed diabetic.

Now that she is off of ZyPrexa, she does not have these extreme shifts (that included shaking, sweating, etc.).

I dare say, that Zyprexa has caused more harm than good for my daughter. Keep in mind I called a ZyPrexa lawsuit attorney in 2005 and asked them if they heard anyone calling in regarding Zyprexa being addictive to the brain; the cause of med-induced psychosis, etc. and they wrote me a letter that said "diabetes" only.
If they were smart, they would look into ALL of the patient complaints with a fine tooth comb and sink Lilly's ship for good.
Besides the blood sugar issues during the daytime, and afternoons, she also had to take Benedryl at school as well as at home, per the larger the dose, her eyes rolled up and would get stuck. She had to be escorted down the 2 story school building by teachers and be sent home, for inability to read a book or write this way. When I complained to (the psych that was fired in 2005)he said it was eye strain. I took her to the general doc and he said it was the ZyPrexa. This was back in 2001.
I spent so many hours in my life in the last 7 years researching the hell out of neuroleptics, the last idea I had was to fly to CA. and sit in the UCLA medical library.
Instead, I spent the last year driving to 4 hospitals in 4 cities, and saw the horrors of living inside institutions.
I do feel the use of psychiatric medications, especially ZyPrexa, contributed to my daughter's unique and complex case history.
There is no gaining back a childhood, a pre-teen years, or high school years. There is no gaining back coming home from a hospital loop after a year and finding out your Graduating Class of Friends are all gone to college.
How does an 18 yr.old move forward with this baggage? Every time I requested to reduce or remove ZyPrexa to my daughter's (now fired psych)doc, and she appeared to end up in a withdrawal state of mind, he critisized ME, and told ME, it was because *I* told him to reduce or remove the Zyprexa. That is where this guilt-trip is stopping. Here and now.
I am tired. I am physically worn out.
I am refusing to carry the guilt-ridden burden of my daughter's medication history on my back any longer.
I am not a doctor. I do not write prescriptions.
I am not the one to blame here. Though the guilt remains. It is a double-edged sword. I actually am the one who pushed for Zyprexa to be studied, and have so many notes and files, and print-offs, what good did it do?

I would like to categorize this medication a toxic substance that should be avoided at all costs.

Listen up folks. This stuff is bad ass, hardcore, brain addicting, brain damaging, metabolic syndrome causing, shit,that in my opinion, could be worse than being on crack.

Done.

Thanks for the outlet here and for the amazing series, The Zyprexa Chronicles.

They should be published.

Posted by: Stephany at December 21, 2006 08:09 AM

Hi. this might not be the best place for this, but: there is a "logical" link between Zyprexa and diabetes that could explain how to prevent it. By logical I mean, "sounds good on paper" but no data yet to prove it.

Each antipsychotic can cause diabetes-- but the key is that they do not all use the same mechanism. Clozril suppresses insulin. But Zyprexa (and Remeron) don't directly affect insulin, but do increase the absorption of fructose (via frutose transporters) and hunger (ghrelin, decreased leptin, etc.)

So maybe the diabetes comes not by insulin resistance, specifically-- but fructose increases. It may be that Zyprexa causes you to eat more, and eat more fructose (i.e. high fructose corn syrup), and that's what sends the blood sugar high, etc, etc.

The question then becomes: if you never eat fructose-- if you eat only Atkins, for example-- would you still get diabetes?

Do people on Zyprexa get diabetes because they are also drinking a lot of soda and juice (high fructose corn syrup?)

I don't know, but I do spend a lot of time telling people not to drink soda and juice.

Posted by: TheLastPsychiatrist at December 21, 2006 11:44 AM

Caught with their pants down. Love it.

Posted by: Priscilla at December 21, 2006 06:27 PM

Last psych,
I feel it was my daughter's diligence in making sure she avoided sugar, and soda, etc during the time she was on Zyprexa, as to why she was never dx w/ diabetes.
She was a smart kid, and had proteins snacks after school, drank water only (2-3 quarts a day her own monitoring system)it was unbelievable the connection she found herself,associated to feeling good and basically did do a Atkins type of diet. She still gained weight though. she dealt with the low blood sugar stuff, She actually wrote a paper at age 17 on how to feel good and diet was key.(she also read labels and never bought anything like cereal etc with sugar in it). I often told her she had a better eating program going than I did.
Now on CLozaril, she wants juice and soda all of the time, so I have had to monitor how much gets into the house.
It is quite an interesting connection, that though she was a super-good monitor of what she ate etc, that she still gained so much weight.

Posted by: Stephany at December 22, 2006 09:30 AM

I LOVE the reporting I've been doing for all these little papers around the city! I wrote a story on the Honors Program, and another on Fairfax Hospital, and it's SO much fun! After break, I'm going to be writing a story on the fancy, shmancy school my doctor's kid goes to, Open Window. Oh, and for the holidays I got his kiddos really cool gifts, and they loved them! His kids are really precocious -- the eldest one was reading by age two and a half, little genius. My doctor's always telling me all the genius things he says. My doctor also gave me pictures of them, and they're SO beautiful! I love them! Anyway, the reporting I've been doing is so fun and fufilling. Even though I'm not the hottest student, at least I have this hobby which I'm absolultly flourishing on.

Posted by: Gwen at December 22, 2006 12:30 PM

It's amazing how little of my recent Overlake hospitlization I remember. I think it's becuase I was taking eight different medications at very high doses, and I was just too druged up. Like, Philip came to visit me (!!!) but I don't remember what we talked about. I remember hiding under tables a lot, and crying a lot, and stuff, but not much else... I remember the staff taking me downstairs to get eggnog lattes every morning... Oh, and Stephany sent me a card (!!!) but I can't remember what I wrote back. The only thing that I really do remember is that the staff were very nice, and it was by far the most PLEASANT hospitilzation I have ever had. But anyway, medications really do wipe out your short-term memory.

Posted by: Gwen at December 22, 2006 04:00 PM

Yeah, I just want to reiterate how nice people are. Philip is nice, Stephany is nice, my doctor is nice, his kids are nice, my cat is nice, my old doctors are nice, my friends are nice, the associate director of the Honors Programs is nice, my editor from my literary magazine is nice, my editors from my little newspapers are nice. Everyone is just so damn nice!!!

Posted by: Gwen at December 22, 2006 04:05 PM

I just found your website. I'm crazy or a psychiatric survivor with several psychiatric labels. Too bad there is no real test to see which one(s) are the correct one(s).I don't take medications or drugs. Congrats on the website and having the courage and strength to question authority.

Posted by: Mark at December 23, 2006 10:21 PM

Gwen,
I am so happy that you are doing well, you are a strong person, and a inspiration to me. I'm glad to see you posting here. :)
--Stephany

Posted by: Stephany at December 24, 2006 03:05 PM

pic1.jpg

Patient Blogs. Sites.
Doctor Blogs. Sites.
Activists. News.
Social Networking. Forums.
Science. Big Pharma. Ethics.
Current Affairs
Seattle Stuff
Smoking. Stuff.

Info
About Furious Seasons
Email
Other Articles
ZYPREXA Documents
Alt ZYPREXA Documents Source
Blakemore-Brown Transcript

 Subscribe in a reader

Search


Recent Entries
$99 Left
$114 To Go
Winter Fundraiser, $134 To Go, Final Day
Ruth Lilly, Eli Lilly Heiress, Prozac Beneficiary Dies At 94
Winter Fundraiser, Final Day, Less Than $200 To Go
UCLA Psychiatrist Criticizes DSM-5
Winter Fundraiser, Barely $200 To Go
Most Popular Posts Of 2009
Winter Fundraiser, Less Than $300 Left, Let's Wrap It Up
Senate Health Care Bill Contains $1.25 Billion Gift To Sen. Stabenow
Travel Day, Comment Approval May Be Intermittent
Winter Fundraiser, Close But Stalled
Senate Health Care Reform Bill Contains Controversial MOTHERS Act, Abortion Study
Adult ADHD And Sleep Problems
Vic Chesnutt Dead At 45, Possible Suicide
Recent Comments

Stephany on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Mark on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Gwen on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Gwen on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Gwen on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Stephany on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Priscilla on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

TheLastPsychiatrist on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Stephany on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Marissa Miller on The Zyprexa Chronicles: Sugary Delights, Lilly Busted By The Times

Archives
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
October 2006
September 2006
August 2006
July 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005
September 2005
Resources
Mental Health America
National Alliance on Mental Illness
Depression and Bipolar Support Alliance
National Institute of Mental Health
McMan Web
Powered by
Movable Type 3.2