October 30, 2006

Antipsychotics Reduce Brain Volume?

This cannot be good. Here's a fresh study, reporting that in macaques given atypical antipsychotics long-term there was a reduction in brain volume. And here's a study from last year reporting pretty much the same thing in monkeys. Both studies found reductions of 10 percent to 20 percent in brain volume. Rhesus macaques are generally considered model systems, or proxies, of human biology. I think I will refrain from further comment.

Posted by Philip Dawdy at October 30, 2006 12:01 AM
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On the other hand, the old standard - Lithium - supposedly INCREASES brain size. See http://dir2.nichd.nih.gov/nichd/usdp/pdf/25LiBDNF.pdf or google "lithium and brain growth" for studies galore.

Posted by: Laura at October 30, 2006 06:43 AM

Well I can say antipsychotic use for 7 years didn't shrink my daughter's brain; due to the neuro-doc saying her brain is a size 10 in a size 9 skull.
Too bad Zyprexa didn't so something positive all those years.

You know, in the days of early airbag-for-cars research, that they strapped dead pigs in carseats and that is how the first generation airbags were tested for human use?

Posted by: Stephany at October 30, 2006 08:23 AM

That's really bad that antipsychotics do that.

Posted by: Gwen at October 30, 2006 09:52 AM

Gwen,
That's why there are so many studies out there...no one knows exactly what happens, and the shrinking of the brain isnt anything to worry about, or think has happpened to you.

Hang in there, you know it is okay to take your time gaining your Degree. Some famous people out there never went to college at all.

You love learning, and writing, and will be successful no matter what you do, because you have a passion for those things.


Just follow your dreams.

~Stephany

Posted by: Stephany at October 30, 2006 10:35 AM

Thank you, Stephany. Really, thank you so much. You're a great support for me. Thanks for being there.

Gwen

Posted by: Gwen at October 31, 2006 06:46 PM

sad, but not surprising.

Posted by: kim at November 3, 2006 11:34 AM

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