September 18, 2006

Aaron Beck Wins Lasker Award

Aaron Beck, generally credited as the father of cognitive behavioral therapy, was awarded the Lasker Prize last week. It's not common for a psychiatrist, which Beck is, to win this nation's premiere medical research award. In fact, it so uncommon that the New York Times saw fit to headline its article "Psychiatrist Is Among Five Chosen For Medical Award." The others were biologists and such.

But it does happen, although usually to some flavor of research neuroscientist, as opposed to straight-up psychiatrists. For example, Seymour Kety, who did important genetic work in schizophrenia and the mapping of cerebral blood flow, won a Lasker in 1999. He was NIMH's first scientific director and is credited as being one of the prime movers in getting psychiatry away from the squishy land of psychoanalysis and onto the dry land of brain-based science. Not that the latter works that much better than the former, but I digress.

It's long overdue recognition for Beck from the medical academy, especially since many in the psych research world pooh-pooh the use of CBT in treating mental illnesses. Whether you can read into this that the medical research elite are turning their eyes in other directions when it comes to addressing mental illnesses is not a place I have the expertise to go.

The reality is that CBT has not been used widely in this country, because America likes its paradigms all or nothing and the dominant paradigm is the pharmacological one. As a result, CBT is not widely available (there are a lot of kissing cousin therapies out there, but none are quite as hard-assed as CBT is about making people address thought patterns) and can be pricey where it is. Nor is CBT as well-researched for its effectiveness as it ought to be.

Where it has been researched, it's generally been found to be effective in treating depression, with or without adjunctive psych meds. Good for depression is what most people will tell you about CBT. But there is some evidence out there that in can be useful in addressing schizophrenia, especially for patients for whom meds aren't cutting it (the old half-working phenomenon). There is also evidence of its efficacy in treating bipolar disorder.

But again there hasn't been nearly enough study of CBT to say how effective it really is. And there are others in the research world who have attacked CBT and the few studies of its effectiveness by calling the studies poorly-constructed. All's fair in love and war, I guess.

As I have noted on this blog on numerous occasions, psych researchers in Britain are now openly questioning the effectiveness of the psychopharmacological paradigm, particularly in treating depression, and that nation's state health system is starting to back off the use of anti-depressants and beginning to embrace the use of CBT. We'll see how that plays out over time.

As I have also noted on this blog to the point of broken-recordom, the molecular era that Kety ushered into being hasn't proved out the way any of us would like it to. Still, American psych researchers, mental health advocates, policy makers and the media all act as if taking mental illness to the level of mental wellness is simply a matter of everyone taking their meds, better meds being developed and the brain being better understood. That's silly. We've been going down that path to the exclusion of any other way of thinking for almost two generations now.

Has anyone got some staggering population-wide results that show just how the current paradigm has redeemed the mentally ill over the long-term? I am not talking about just keeping someone alive and now-psychotic, for example, by doping them to the max. I am talking in lives lived well and lives rehabilitated above the status of janitor. We've been doing shit this way for closing on 30 years. Where are the results? Can anyone show me where the rate of suicide has radically decreased in this country in the last 50 years?

Beck is now 85-years-old. He deserves to be awarded the Nobel Prize in Medicine before he dies.

Posted by Philip Dawdy at September 18, 2006 12:01 AM
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Comments

i totally agree, it is way more than meds, and half-lives lived on them, is less than what the goal should be.

Just being "woken up" with meds isnt gonna cut it.


What happens next docs?

(silence).

Posted by: Stephany at September 18, 2006 05:56 PM

Hi, Philip. Here's the study that cracked it wide open:

http://content.nejm.org/cgi/content/abstract/342/20/1462?maxtoshow=&HITS=20&hits=20&RESULTFORMAT=&fulltext=Keller&searchid=1058637220071_5446&stored_search=&FIRSTINDEX=0&sortspec=Score+desc+PUBDATE_SORTDATE+desc&fdate=1/1/2000&tdate=7/31/2000&journalcode=nejm

In a nutshell: A form of CBT and an antidepressant were each about as effective with depressed patients. That part of the study was predictable. What raised eyebrows was that the two treatments together resulted in exceptionally high response and remission rates.

A drug company spent more than $20 million on the study. It's a major trial, highly-powered. We need way more studies like this.

CBT has definitely arrived. As well as for depression, it is now being used to nip mania episodes in the bud. Check out Monica Basco's Bipolar Workbook.

Posted by: John McManamy at September 18, 2006 06:26 PM

I have to follow up on my post above, that says "what happens next docs?" (silence).

What I am finding out, is that their primary goal is to get the patient back to what they call "baseline" or "close to baseline", even if they didn't know what the person's base was prior, to for instance, a year-long psychotic break.

What happened in real-time next for my daughter, was to be sent to a residential housing situation.

That is a wonderful service for the age population that is housed where she lives, but I can tell ya, this is not about rehab into the world for any of them.

It's gonna be up to me to find the CBT or the DBT, assist and make sure she gets her HS diploma, so she can possibly get a foothold back into life.

The services out there are rare and hard to find, my daughter is young and fortunate to gain them so young, for that I am grateful, as well as for the meds that appear to have "awakened" her....but she is far from having a quality life right now.

To wake up, and be drugged up to the max, pale with tremors, and fatigue....well, that is not how I hope she lives the rest of her life.


It is how I have seen many others live theirs, and I'm not too happy about what I have seen in the mental health arena.


Enormous change needs to happen. If an 18 year old can be set aside to stare at a TV all day in a residential housing setting, and doctors stop there, just because they reached a "baseline"--- calling THAT victorious....well, I don't.

Posted by: Stephany at September 19, 2006 08:03 AM

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