July 28, 2006The Usual ShitI was interviewing a doctor today on a subject removed from mental illness. A nice change. Towards the end of our chat, we got into a short sidebar about alternative treatments for cancer. He made the point that while he could see the usefulness of medical marijuana that he felt it was inappropriate medicine because it is smoked (not always, but most of the time). His argument was that we should do nothing to encourage smoking of any kind in this country because of what he deemed were unacceptable side effects. I went into skeptic mode for a minute just to see where it would get me. But we give patients all kinds of medications that have unhealthy side effects every day, in some cases for long periods of time, I pointed out, so what's the problem? He asked me for an example of a med that caused patients all kinds of problems. Zyprexa, I said. And pointed out what is known about deaths tied to its use, its diabetes-inducing ways and so on. He paused for a moment. Then he said, "On the whole, Zyprexa is therapeutic." I let that bit of mythology go. He's an important doctor, an internist by training, who was a major muckety-muck at one of America's top 10 medical schools and is, now, head of research at one of the nation's largest HMOs. I am not naming him here, because we really didn't get to flesh out what he meant and because I want the guy to talk to me again. The guy is what's known as a thought leader. But let's put it this way: If you got 1,000 Zyprexa patients to testify before the FDA about the nasty effects of the drug, their opinions and experiences would be swept away in two minutes by a few sentences from this doctor. He's that big of a big shot. Why aren't people like him listening to psych patients and being honest with what effectiveness studies are showing about Zyprexa and other pysch meds? Why hasn't the CATIE study sunk into the pronouncements of thought leaders? This isn't a minor question. Until people like him, in a position to truly influence the debate on health care in this country, get honest about what's up with meds, then we are fucked. Or we are going to have to find another way to change the game without the help of him and his colleagues. Posted by Philip Dawdy at July 28, 2006 12:01 AM
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"...we give patients all kinds of medications that have unhealthy side effects every day..." That's probably one of the most intelligent arguments for the legalization of medical marijuana I've ever heard! Posted by: Gwen at July 28, 2006 11:25 AMThen get more than 1000. Posted by: Stephany at July 28, 2006 06:03 PMHi, Philp. First, I'm an anti-smoking Nazi. Second, I would hand out cigarettes free to anyone with schizophrenia. Okay, I exaggerate slightly, but there's very good scientific evidence showing that nicotine action on the cellular level can clear up cognition. To remove a cigarette from someone with schizophrenia could be a breach of the "Do no harm" rule. So here's the deal: With cigarettes - a few precious moments of cleared up cognition in return for risk of lung cancer. A reasonable choice for some. With Zyprexa - a miracle drug for some in return for risk of diabetes and certainty of a lot of metabolic crap. Again, a reasonable choice for some. My guess is your internist contact is extremely naive. He works in a specialty where meds typically hit their main target with little or no collateral damge. An antipsychotic, on the other hand, works on a dozen targets at once, 11 which have nothing to do with getting us better. Thus, the high cost of doing business. Yes, there are meds in other branches of medicine that can cause extreme side effects, but these tend to be the exceptions. Some individuals may decide that Zyprexa is their best option. It's all about informed choice. Posted by: John McManamy at July 30, 2006 08:04 AMPer a personal 6 year study of ZyPrexa, and observations of the use of it with my daughter, ZyPrexa is no wonder drug, and possibly the reason she endured a most unfortunate agitated life until it's removal when she then suffered a near year long battle of psychosis, not to mention the 50 pounds she gained on a 5' 3" body frame, and all of this during the most influential years of a young person's life: junior high and high school. I took zyprexa starting in 1996 the year the FDA approved it, which was ineffective for my condition and gave me diabetes. Zyprexa is the product name for Olanzapine,it is Lilly's top selling drug.It was approved by the FDA in 1996 ,an 'atypical' antipsychotic a newer class of drugs without the motor side effects of the older Thorazine.Zyprexa has been linked to causing diabetes and pancreatitis. Zyprexa, which is used for the treatment of psychiatric disorders, such as schizophrenia and bipolar disorder, accounted for 32% of Eli Lilly's $14.6 billion revenue last year. Did you know that Lilly made nearly $3 billion last year on diabetic meds, Actos,Humulin and Byetta? Yes! They sell a drug that can cause diabetes and then turn a profit on the drugs that treat the condition that they may have caused in the first place! I was prescribed Zyprexa from 1996 until 2000. All the psychiatrist I've interviewed and the information on line presents zyprexa as a worse offender than the other Atypicals such as seroquel.My doctor has stopped prescribing zyprexa altogether. The PDR classifies zyprexa as 'severe' for causing weight gain and diabetes and seroquel as 'moderate'. Of course the 50 year old Thorazine didn't cause diabetes and is many times cheaper but it could cause tardive dyskinesia. Where Eli Lilly's negligence comes in,is their KNOWING and not informing consumers (black box warning) until the FDA demanded it. Lilly's incentive not to readily disclose is they had billions coming in from state medicaid scripts. I'm surviving the suicide of my mom -- and was prescribed Zyprexa to treat my bi-polar. I do believe STRONGLY in the power of anti-depressants to save lives, but atypical anti-psychotics have literally ravaged me. Within days of increasing my dose of Zyprexa to 5mg, I had severe edema -- well over-the-knee, flu-like symptoms, severe shakes, and extreme urges to hurt myself. I also have 3 new cavities suddenly and wonder if that has anything to do with the 3 weeks I took Zyprexa. A big symptom of my illness is "pea-soup brain" and the Zyprexa did get rid of that, but at overwhelming costs. It doesn't matter if the pea soup brain is gone if I suddenly start to self-injure, does it?? On the subject -- Seroquel gave me horrific TMJ and a host of other symtoms that have luckily gone away. I'm still carrying around the 70 pounds I gained with the help of Depakote. When I look in the mirror at the physical ravages from mental illness and the physical ravages from the anti-psychotic drugs meant to treat some symptoms -- the anti-psychotic drugs win, by far. If we're looking at lethality issues, both seem to be killing slowly. Mental illness with depression, poor choices and general sense of hopelessness. The anti-psychotic drugs with morbid obesity and damage to all my systems. I almost went blind taking Abilify. Of course, depression and bi-polar kills quickly, too. And for that, I'm lucky the drugs HAVE saved me. But, that's the anti-depressant class. Europeans have a better outcome for their psychotic patients and interestingly, their anti-psychotic use is substantially lower. Posted by: Sunnie at April 17, 2007 01:50 PMSunnie, |
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