April 18, 2006

My Usual Skepticism On Genetic Research

Scientists think they've identified a strong candidate gene for schizophrenia and are beginning to get an understanding of how it affects the brain. That's fascinating, but it doesn't mean squat for schizophrenics today since it would be a good 20 years until, should it be a valid theory, it turns into a fix. Until then, the state of the art isn't too promising for patients. Haven't we got something more workable and tolerable to offer schizophrenics in the meantime than Zyprexa and Risperdal? Can't we do the equivalent of the CATIE study on how schizophrenics who have gotten better got that way? Josh Nash didn't win that Nobel Prize because of Haldol, after all.

Posted by Philip Dawdy at April 18, 2006 12:03 AM
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Seroquel became the new popular antipsychotic, along with Abilify, thus the decline in Zyprexa sales. Coming soon from Solvay, the manufacturer of Lithobid and Luvox is a new antipsychotic that surely will kick the rest down the list of overly prescribed anitpsychotics, once it is available to the docs and they get all of the free samples, pens, notepads and clipboards. Unfortunately, mind altering drugs that leave lives altered sometimes for good and sometimes not, is a big business. Whatever sells gets the attention. In the meantime, it is the human beings, and their lives that are being sold to the highest bidder. I project the newest antipsychotics will be 'deemed promising with less side effects for those suffering with XYZ'.Seems it always starts that way.

http://www.drugdevelopment-technology.com/projects/bifeprunox/

"Bifeprunox mesilate is a novel atypical antipsychotic agent under development by Solvay Pharmaceuticals as a treatment for schizophrenia and potentially conditions such as bipolar disorder."..."Bifeprunox is one four antipsychotic drugs currently in advanced-stage development for treatment of schizophrenia. Analysts believe that of the four, bifeprunox is the most likely to succeed given its promising efficacy and side-effect profile. If approved in 2006 it will join a very crowded market. In the US six atypical agents currently compete for a share of the antipsychotic sector, while in Europe seven atypical agents are now in routine clinical use."

Of course Ive been told that lower stress levels help prevent psychotic episodes. (really? thank you doctor)No fine tuned answers to any of this shit.

Posted by: Stephany at April 19, 2006 08:09 AM

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